Gun advice for New Orleans-type situations
A shotgun or rifle in your bedroom (or anywhere else) is of limited utility if an attack comes when you are in some other part of your home. Likewise a shotgun or rifle may be difficult to bring into play in a car – especially if there is only you and you are driving your car. If you have multiple people in the vehicle a shotgun or rifle for each may be viable but even so may be much more difficult to bring into play. If you have a pick-up truck my off-hand recommendation would be for the driver and passenger to have handguns (w/ long guns stowed behind the seat or in a rack in the event you have time to deploy out of the vehicle) and long guns for anyone who is in the bed of the truck, though they all should also have a holstered handgun.
As to the species of handgun, I would recommend a high-capacity semi-auto in a caliber not less than .40 S&W or, at least 9mm. There are zillions of different brands on the market that are excellent and choosing between them is either a matter of personal taste or of expertise exceeding mine. My personal experience is most extensively with the Glock and Sig-Sauer 225 in 9mm. and Sigma in .40 S&W; all of which are fine.
SPECIAL CIRCUMSTANCES: If you are attacked from 100 yards or more away (a highly unlikely scenario) you will need a rifle. I have much less experience w/ these but would recommend something like the Ruger Ranch Rifle or an H&K high cap semi-auto or other quality weapon in a caliber exceeding 223.
For stopping power at short range nothing beats a shotgun loaded w/ slugs or, at worst, large buckshot. But you would only select a shotgun in the very unusual situation in which you: (a) can predict the time you will be attacked so you can be sure to have the shotgun w/ you; and (b) can predict that the attack will come from a short enough range that a shotgun is effective.